(a) Absolute contraindications to LTX

(i) Malignant diseases in the past 2 years
(ii) Untreatable severe dysfunction of another important organ system (heart, liver, and kidney) not amenable to surgical correction/combined TX
(iii) Chronic, incurable extrapulmonary infection
(iv) Severe deformations of chest and spine
(v) Severe or symptomatic osteoporosis
(vi) Lack of adherence to therapy
(vii) Untreatable mental disorders combined with lack of cooperation
(viii) Addictive disorder currently or during the past 6 months (tobacco and alcohol addiction, substance abuse)