Table 5.
1st month | 2nd–6th month | >6 months |
---|---|---|
Nosocomial infections* Respiratory tract infections Surgical site infections Urinary tract infections Catheter infection, sepsis |
Reactivation of latent infections + opportunistic infections | Community-acquired infections/pneumonia |
| ||
Related more to surgery and intensive care | Related more to immunosuppression | |
| ||
CF lung pathogens: Pseudomonas spp. Burkholderia cepacia complex B. gladioli; NTM Other bacteria: S. aureus Enterobacteriaceae Enterococci Acinetobacter spp. Fungi: Candida spp. (Aspergillus spp.) Viruses: Herpes simplex virus Respiratory viruses |
Viruses: Cytomegalovirus Epstein-Barr virus Herpes simplex virus Varicella Zoster virus Opportunists: P. jirovecii Toxoplasmosis Aspergillus spp. Nocardia Listeria Mycobacteria (especially NTM) CF-lung pathogens: Pseudomonas spp. Burkholderia spp. |
Viruses: Epstein-Barr virus Respiratory viruses Respiratory bacteria: S. pneumonia H.influenzae C. pneumoniae M. pneumoniae and others CF lung pathogens: Pseudomonas spp. Burkholderia spp. Fungi: Aspergillus spp. |
| ||
C. difficile infection** | Late-onset C. difficile infection |
*May occur also in later periods after LTX depending on prolonged or recurrent hospitalisation and the presence of medical devices.
**Highest incidence within the first 3 up to 12 months after LTX in association with broad antimicrobial therapy and intense immunosuppression.