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. Author manuscript; available in PMC: 2014 Apr 16.
Published in final edited form as: Development. 2008 Mar 5;135(8):1547–1557. doi: 10.1242/dev.015867

Figure 9. CHR2-induced neuronal activation drives dFMRP-dependent pruning.

Figure 9

A) Single cell MARCM clones expressing channelrhodopsin-2 (CHR2) in control or in dfmr1 null backgrounds, with animals grown on food containing all-trans retinal (ATR) or ethanol (ETOH vehicle). Post-eclosion animals (<12 hours after eclosion) were stimulated with 470 nm light at 1Hz pulses for 6 hours. Scale bar=10μm. Quantified total axon branch number (B) and <5μm branch number (C) of CHR2-expressing MARCM clones after blue light stimulation. Horizontal bars are the mean for each data set. Significance: 0.01<P<0.05 (*).