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Activity of ALDH3A1 in cell lysates. A549, SF767, and CCD-13Lu cell lysate activity as well as recombinant ALDH3A1 activity was tested in the presence of 1.5 mM NADP+ and 1 mM benzaldehyde and in the presence and absence of 10 μM CB7 and its analogues. CCD-13Lu did not show any NADP+ catalyzed benzaldehyde oxidation. The p-values were calculated using the Student’s t test comparing activity in the absence and presence of ALDH3A1 inhibitor (∗, p < 0.0001, n = 3).
