. 2014 Jan 4;57(2):449–461. doi: 10.1021/jm401508p

Table 1. Structure–Activity Relationships for Analogues of CB7^a.

graphic file with name jm-2013-01508p_0011.jpg

Values in parentheses represent standard error. NI stands for no inhibition, and NI(A) stands for no inhibition but very weak activation (∼20% at 100 μM). Residues of ALDH3A1 that are in close contact with CB7 are shown in yellow boxes. None of the compounds tested had any inhibitory effect on ALDH1A2, ALDH1A3, or ALDH1B1. Figure was generated using ChemBioDraw Ultra 12.0.

Table 1. Structure–Activity Relationships for Analogues of CB7a.

Table 1. Structure–Activity Relationships for Analogues of CB7^a.