Table 2.
The comparative clinical and laboratory data of HD patients.
| Parameter | Group 1 (n = 92) | Group 2 (n = 81) | Group 3 (n = 74) | Group 4 (n = 49) | P |
|---|---|---|---|---|---|
| Hemoglobin (g/dL) | 12.9 ± 0.8 | 13.1 ± 1.0 | 13.0 ± 1.0 | 12.8 ± 0.7 | >0.05* |
| Hematocrit (%) | 41.8 ± 4.6 | 43.7 ± 5.8 | 40.2 ± 4.2 | 39.7 ± 4.1 | >0.05* |
| RDW (%) | 13.2 ± 1.4 | 14.7 ± 1.6‡ | 17.8 ± 1.9§ | 18.5 ± 2.0¶ | 0.014* |
| MCV (fL) | 85.9 ± 7.4 | 83.7 ± 6.1 | 88.5 ± 5.2 | 91.4 ± 6.0 | >0.05* |
| MCH (pg) | 28.4 ± 2.7 | 27.9 ± 3.0 | 31.3 ± 2.9 | 30.2 ± 3.5 | >0.05* |
| MCHC (g/dL) | 34.5 ± 1.4 | 35.2 ± 1.7 | 34.0 ± 1.3 | 33.1 ± 1.0 | >0.05* |
| TS (%) | 33.8 ± 17.1 | 36.1 ± 14.7 | 34.5 ± 19.8 | 38.6 ± 18.4 | >0.05† |
| Ferritin (ng/mL) | 627.1 ± 112.6 | 734.6 ± 140.3 | 662.8 ± 130.8 | 704.4 ± 142.9 | >0.05* |
| Creatinine (mg/dL) | 8.9 ± 3.1 | 10.5 ± 3.9 | 8.2 ± 4.0 | 9.6 ± 4.8 | 0.026† |
| Calcium (mg/dL) | 9.1 ± 1.6 | 9.6 ± 1.8 | 8.9 ± 1.3 | 9.2 ± 1.6 | >0.05* |
| Phosphate (mg/dL) | 5.1 ± 1.0 | 5.3 ± 1.1 | 4.5 ± 0.8 | 4.7 ± 0.9 | >0.05* |
| Total cholesterol (mg/dL) | 178.8 ± 60.1 | 193.7 ± 81.5 | 162.4 ± 65.8 | 155.7 ± 58.1 | 0.045† |
| Triglyceride (mg/dL) | 183.2 ± 76.4 | 191.3 ± 62.8 | 154.4 ± 58.7 | 159.2 ± 65.5 | 0.038† |
| HDL-cholesterol (mg/dL) | 32.1 ± 7.4 | 37.2 ± 8.5 | 33.8 ± 6.8 | 30.7 ± 6.2 | >0.05* |
| LDL-cholesterol (mg/dL) | 122.3 ± 39.7 | 145.7 ± 46.8 | 110.5 ± 37.2 | 103.4 ± 48.7 | 0.029† |
| Albumin (g/dL) | 4.1 ± 0.4 | 3.8 ± 0.3 | 3.3 ± 0.3 | 3.0 ± 0.2 | 0.035* |
| CRP (mg/L) | 3.5 ± 2.4 | 7.9 ± 2.1 | 4.1 ± 2.7 | 9.6 ± 4.2 | 0.024* |
| iPTH (pg/mL) | 286.5 ± 132.7 | 261.3 ± 102.2 | 278.4 ± 130.1 | 301.2 ± 119.7 | >0.05† |
| URR (%) | 0.71 ± 0.05 | 0.74 ± 0.06 | 0.69 ± 0.03 | 0.70 ± 0.04 | >0.05* |
| kT/V | 1.54 ± 0.21 | 1.50 ± 0.26 | 1.48 ± 0.31 | 1.53 ± 0.25 | >0.05* |
*One-way ANOVA (for parametric data).
†Kruskal Wallis test (for nonparametric data).
‡RDW difference between group 1 and group 2, post hoc P = 0.028 (Tukey's test).
§RDW difference between group 3 and group 1, post hoc P = 0.017; group 3 versus group 2, post hoc P = 0.031 (Tukey's test).
¶RDW difference between group 4 and group 1, post hoc P = 0.004; group 4 versus group 2, post hoc P = 0.019; group 4 versus group 3, post hoc P = 0.041 (Tukey's test).
RDW: red cell distribution width, MCV: mean corpuscular volume, MCH: mean cell hemoglobin, MCHC: mean corpuscular hemoglobin concentration, TS: transferrin saturation, LDL: low-density lipoprotein cholesterol, HDL: high-density lipoprotein, CRP: C-reactive protein, iPTH: intact parathyroid hormone, and URR: urea reduction ratio.