Table 1.
Concentrations (µg/mL) | Acarbose (positive control) | Total extract | Psoralen (1) | 5-methoxypsoralen (2) | Imperatorin (4) | Isooxypeucedanin (5) | Oxypeucedanin hydrate (8) |
---|---|---|---|---|---|---|---|
α-amylase inhibition% | |||||||
10 | 32.20 ± 1.29a | 31.20 ± 2.34a | 16.48 ± 0.98e | 17.59 ± 0.60e | 28.27 ± 2.97d | 19.21 ± 1.08e | 18.40 ± 1.10e |
50 | 35.19 ± 348c | 29.33 ± 4.13a | 24.78 ± 2.24b | 28.70 ± 1.04a | 34.16 ± 1.04c | 22.11 ± 1.22b | 23.33 ± 2.45b |
100 | 47.37 ± 4.15g | 45.00 ± 5.06g | 28.34 ± 1.89e | 34.29 ± 3.11d | 45.15 ± 6.18g | 24.14 ± 2.00f | 25.30 ± 1.99f |
500 | 52.55 ± 4.49c | 49.97 ± 6.19c | 39.65 ± 2.80b | 45.12 ± 3.33a | 52.26 ± 5.69c | 39.77 ± 3.20b | 37.08 ± 2.00b |
1000 | 71.34 ± 2.65d | 70.77 ± 8.87d | 50.50 ± 1.10b | 58.10 ± 2.14a | 67.56 ± 4.67c | 51.20 ± 3.40b | 53.50 ± 1.10b |
LSD 5% | 5.88 | 4.99 | 3.9 | 4.32 | 5.18 | 4.99 | 7.90 |
| |||||||
α-glucosidase inhibition% | |||||||
10 | 29.94 ± 2.04b | 28.89 ± 6.67b | 23.00 ± 3.03c | 25.15 ± 3.08c | 28.89 ± 2.90b | 24.33 ± 2.00c | 24.28 ± 2.13c |
50 | 43.25 ± 3.09c | 40.20 ± 6.79c | 33.55 ± 4.73b | 34.81 ± 23.68b | 37.76 ± 6.18a | 32.12 ± 1.28b | 31.68 ± 5.00b |
100 | 52.45 ± 4.67d | 47.30 ± 5.58c | 41.65 ± 2.00a | 45.20 ± 2.45d | 46.56 ± 2.46c | 39.90 ± 6.50a | 40.23 ± 4.56a |
500 | 69.14 ± 4.15c | 56.25 ± 7.29b | 42.75 ± 1.79a | 48.00 ± 2.78d | 55.67 ± 6.78b | 41.51 ± 2.88a | 42.91 ± 2.60a |
1000 | 85.33 ± 2.47c | 74.25 ± 8.09b | 59.85 ± 2.90e | 64.39 ± 1.78d | 69.66 ± 3.67b | 52.31 ± 2.50a | 51.67 ± 2.60a |
LSD 5% | 5.90 | 10.99 | 4.90 | 5.93 | 5. 94 | 5.77 | 5.99 |
| |||||||
% | |||||||
10 | 45.85 ± 2.90a | 42.20 ± 5.57a | 17.90 ± 4.32c | 23.56 ± 4.31b | 34.54 ± 4.20d | 19.90 ± 6.22c | 18.90 ± 2.32c |
50 | 55.90 ± 4.70a | 50.00 ± 8.90d | 35.35 ± 9.00b | 34.77 ± 5.90b | 39.79 ± 5.90c | 33.90 ± 4.40b | 33.26 ± 5.06b |
100 | 59.00 ± 6.10a | 55.67 ± 8.80h | 37.86 ± 5.48c | 39.46 ± 6.35b | 53.90 ± 6.80d | 36.30 ± 4.35c | 35.80 ± 5.67c |
500 | 78.56 ± 5.78a | 77.30 ± 4.56a | 54.33 ± 5.41c | 62.34 ± 5.99b | 69.90 ± 6.50d | 50.70 ± 4.71c | 48.70 ± 3.56e |
1000 | 83.66 ± 6.51a | 78.66 ± 9.01h | 56.00 ± 5.01c | 65.31 ± 4.17b | 72.86 ± 4.41d | 54.34 ± 4.57c | 56.09 ± 4.41c |
LSD 5% | 11.00 | 11.00 | 13.1 | 12.7 | 11.20 | 12.99 | 12.96 |
Data are means ± SD of three replicates in each group. Statistical analysis is carried out using CoStat Computer Program coupled with post hoc (least significance difference LSD), where the unshared letter is significantly different at P ≤ 0.05.