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. 2014 Mar 31;2014:480545. doi: 10.1155/2014/480545

Table 1.

In vitro carbohydrate metabolizing enzymes inhibition activities (%) of Ducrosia anethifolia total extract and isolated linear furanocoumarins.

Concentrations (µg/mL) Acarbose (positive control) Total extract Psoralen (1) 5-methoxypsoralen (2) Imperatorin (4) Isooxypeucedanin (5) Oxypeucedanin hydrate (8)
α-amylase inhibition%
10 32.20 ± 1.29a 31.20 ± 2.34a 16.48 ± 0.98e 17.59 ± 0.60e 28.27 ± 2.97d 19.21 ± 1.08e 18.40 ± 1.10e
50 35.19 ± 348c 29.33 ± 4.13a 24.78 ± 2.24b 28.70 ± 1.04a 34.16 ± 1.04c 22.11 ± 1.22b 23.33 ± 2.45b
100 47.37 ± 4.15g 45.00 ± 5.06g 28.34 ± 1.89e 34.29 ± 3.11d 45.15 ± 6.18g 24.14 ± 2.00f 25.30 ± 1.99f
500 52.55 ± 4.49c 49.97 ± 6.19c 39.65 ± 2.80b 45.12 ± 3.33a 52.26 ± 5.69c 39.77 ± 3.20b 37.08 ± 2.00b
1000 71.34 ± 2.65d 70.77 ± 8.87d 50.50 ± 1.10b 58.10 ± 2.14a 67.56 ± 4.67c 51.20 ± 3.40b 53.50 ± 1.10b
LSD 5% 5.88 4.99 3.9 4.32 5.18 4.99 7.90

α-glucosidase inhibition%
10 29.94 ± 2.04b 28.89 ± 6.67b 23.00 ± 3.03c 25.15 ± 3.08c 28.89 ± 2.90b 24.33 ± 2.00c 24.28 ± 2.13c
50 43.25 ± 3.09c 40.20 ± 6.79c 33.55 ± 4.73b 34.81 ± 23.68b 37.76 ± 6.18a 32.12 ± 1.28b 31.68 ± 5.00b
100 52.45 ± 4.67d 47.30 ± 5.58c 41.65 ± 2.00a 45.20 ± 2.45d 46.56 ± 2.46c 39.90 ± 6.50a 40.23 ± 4.56a
500 69.14 ± 4.15c 56.25 ± 7.29b 42.75 ± 1.79a 48.00 ± 2.78d 55.67 ± 6.78b 41.51 ± 2.88a 42.91 ± 2.60a
1000 85.33 ± 2.47c 74.25 ± 8.09b 59.85 ± 2.90e 64.39 ± 1.78d 69.66 ± 3.67b 52.31 ± 2.50a 51.67 ± 2.60a
LSD 5% 5.90 10.99 4.90 5.93 5. 94 5.77 5.99

%
10 45.85 ± 2.90a 42.20 ± 5.57a 17.90 ± 4.32c 23.56 ± 4.31b 34.54 ± 4.20d 19.90 ± 6.22c 18.90 ± 2.32c
50 55.90 ± 4.70a 50.00 ± 8.90d 35.35 ± 9.00b 34.77 ± 5.90b 39.79 ± 5.90c 33.90 ± 4.40b 33.26 ± 5.06b
100 59.00 ± 6.10a 55.67 ± 8.80h 37.86 ± 5.48c 39.46 ± 6.35b 53.90 ± 6.80d 36.30 ± 4.35c 35.80 ± 5.67c
500 78.56 ± 5.78a 77.30 ± 4.56a 54.33 ± 5.41c 62.34 ± 5.99b 69.90 ± 6.50d 50.70 ± 4.71c 48.70 ± 3.56e
1000 83.66 ± 6.51a 78.66 ± 9.01h 56.00 ± 5.01c 65.31 ± 4.17b 72.86 ± 4.41d 54.34 ± 4.57c 56.09 ± 4.41c
LSD 5% 11.00 11.00 13.1 12.7 11.20 12.99 12.96

Data are means ± SD of three replicates in each group. Statistical analysis is carried out using CoStat Computer Program coupled with post hoc (least significance difference LSD), where the unshared letter is significantly different at P ≤ 0.05.