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. 2014 Mar 19;81(6):1290–1296. doi: 10.1016/j.neuron.2014.01.005

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© 2014 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).

PMC Copyright notice

Plasticity Induction Affects Electrical but Not Chemical Synapse

(A) Induction: lower intensity stimulation and current pulses were combined to cause spiking and synaptic responses (100 pairings at 1 Hz). (B) Sample pair: coupling was depressed (left traces) after pairing, but the synaptic response (right traces) in both cells remained stable. (C) Time course of the normalized EPSP amplitude (averaged across both cells; n = 8 experiments) and the coupling coefficient (n = 11). (D) Population data for the ratio of normalized coupling coefficients after and before induction.