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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Behav Genet. 2014 Jan 23;44(2):113–125. doi: 10.1007/s10519-014-9641-2

Table 5.

Highest ranked CpGs associated with Bayley-III Receptive Communication scores at one year of age (p < 0.0001)

CpG Region Gene Gene role CpG
Island		 p Value Beta b R2
cg24450631 3 IGF2BP2 Insulin-like growth factor 2 mRNA binding protein 2 isoform b Yes 2.48 × 10−5 1.39 0.35 0.58
cg20592700 7 WIPI2 WD40 repeat protein interacting with phosphoinositides 2 Yes 7.34 × 10−5 1.18 0.40 0.57
cg15513137 2 SCN2A2 Sodium channel; voltage-gated; type II; alpha 2 No 7.92 × 10−5 −1.32 −0.38 0.57
cg25984124 20 CDS2 Phosphatidate cytidylyltransferase 2 No 9.72 × 10−5 2.10 0.44 0.60

P value regression p value for a methylation probe, Beta partial regression coefficient, b standardized partial regression coefficient, R2 coefficient of determination (ratio of “explained variance” to total variance) for the full multiple regression model which included non-genetic covariates and the logit transformed methylation beta-value for a probe (one at a time)