Table 1.

Brain activity during cue/anticipation that shows a significant amygdala-mediated relationship with reappraisal success (a*b mediation path)

Mediation path	x	y	z	k	a*b			a			b			c'			c
					Eff	t	P	Eff	t	P	Eff	t	P	Eff	t	P	Eff	t	P
Negative-mediated relationship
RH Sup frontal gyrus (BA 10)	24	62	18	94	−1.22	−2.35	0.03	2.46	2.79	0.01	−0.48	−2.64	0.01	−0.25	−0.22	0.83	−1.48	−1.27	0.22
RH Sup Frontal Gyrus (BA 8)	34	21	54	96	−1.48	−2.34	0.03	2.40	2.47	0.02	−0.61	−3.11	0.00	1.04	0.92	0.37	−0.44	−0.40	0.69
RH Sup temporal gyrus (BA 40)	48	−48	23	174	−1.84	−2.33	0.03	2.99	2.58	0.02	−0.62	−2.96	0.01	1.37	1.02	0.32	−0.47	−0.40	0.69
LH precentral gyrus (BA 4)	−21	−21	54	74	−2.82	−2.27	0.03	5.78	2.62	0.01	−0.49	−2.54	0.02	−0.64	−0.12	0.91	−3.47	−1.44	0.16
RH post cingulate gyrus (BA 31)	17	−41	32	105	−1.06	−2.25	0.03	2.20	2.59	0.02	−0.48	−2.67	0.01	−0.31	−0.22	0.83	−1.37	−1.26	0.22
RH postcentral gyrus (BA 3)	31	−34	50	50	−1.58	−2.25	0.03	3.10	2.79	0.01	−0.51	−2.47	0.02	0.03	0.00	1.00	−1.55	−1.49	0.15
Positive-mediated relationship
RH Insula (BA 13)	41	0	−5	71	1.83	2.37	0.03	−2.78	−2.78	0.01	−0.66	−2.82	0.01	−1.79	−1.09	0.28	0.04	0.04	0.97
LH insula (BA 13)	−48	10	−5	59	1.40	2.35	0.03	−2.36	−2.78	0.01	−0.58	−2.79	0.01	−0.80	−0.74	0.47	0.60	0.73	0.47
RH anterior lobe cerebellum	3	−69	−36	126	1.18	2.36	0.03	−2.18	−2.63	0.01	−0.54	−2.76	0.01	−0.48	−0.51	0.62	0.70	0.72	0.48
RH anterior lobe cerebellum	14	−48	−41	56	1.39	2.31	0.03	−2.34	−2.57	0.02	−0.60	−2.76	0.01	−0.95	−0.86	0.40	0.44	0.43	0.67

Regions are whole-brain FWE-corrected at P < 0.05, two-tailed, with thresholds of P < 0.05 and k ≥ 50 voxels. Coordinates are in MNI space. For each cluster, path coefficients, t-scores and significance levels are shown for each mediation path.