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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Nat Genet. 2014 Feb;46(2):100–106. doi: 10.1038/ng.2876

1. MLMe increases power but MLMi reduces power vs. linear regression.

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We report χ2 association statistics at 500 causal markers for MLMi vs. linear regression and MLMe vs. linear regression for one simulation with genotypes from ref. 24 data and simulated phenotypes for N=10,000 samples. For MLMe, the 500 causal markers were always excluded from computing the GRM.