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. 2014 Apr 16;9(4):e93357. doi: 10.1371/journal.pone.0093357

Table 1. Concomitant associated diseases and medication at baseline.

Survivor (n = 102) Cardiovascular Death (n = 49) Total (n = 151) Sign.
Age (years) 64.3±10.2 72.3±9.3 66.9±10.6 <0.001
BMI 26.9±3.0 26.3±3.3 26.7±3.1 0.318
Male gender n (%) 73 (71.6) 28 (57.1) 101 (66.9) 0.097
Hypertension n (%) 76 (74.5) 46 (93.9) 122 (80.8) 0.004
Smoker n (%) 80 (78.4) 26 (53.1) 106 (70.2) 0.002
Current smoker n (%) 42 (41.2) 12 (24.5) 54 (35.8) 0.048
Diabetes mellitus n (%) 27 (26.5) 22 (45.8) 49 (32.7) 0.025
Hyperlipidemia n (%) 54 (52.9) 24 (49) 78 (51.7) 0.729
Hemoglobin (g/dl) 14.2±1.5 13.0±1.7 13.8±1.6 <0.001
Homocysteine (µmol/l) 15.0±4.8 16.9±4.6 15.5±4.8 0.048
Total cholesterol (mg/dl) 208.2±47.5 196.7±51.5 204.6±48.9 0.196
HDL cholesterol (mg/dl) 50.8±14.6 49.6±15.2 50.5±14.8 0.650
LDL cholesterol (mg/dl) 124.4±39.4 113.9±38.1 121.2±39.2 0.149
Lp (a) (mg/dl) 13.1 (9.5, 50.5) 18.6 (10.0, 45.7) 13.3 (9.5, 47.6) 0.310
High sensitive CRP (mg/l) 4.0 (2.0, 8.8) 5.5 (2.9, 8.8) 4.2 (2.2, 8.8) 0.140
Creatinine Clearance (ml/min/1.7) 70.6±23.5 56.9±26.2 66.1±25.1 0.002
HbA1c (%) 5.7 (5.4, 6.3) 6.1 (5.5, 6.9) 5.8 (5.4, 6.5) 0.046
Cerebrovascular disease n (%) 52 (51.0) 23 (46.9) 92 (50.0) 0.881
Coronary artery disease n (%) 20 (19.6) 12 (24.5) 39 (21.2) 0.790
Statin n (%) 49 (48.0) 24 (49.0) 86 (46.7) 0.643
Aspirin n (%) 75 (73.5) 31 (63.3) 128 (69.6) 0.405
Clopidogrel n (%) 8 (7.8) 6 (12.2) 17 (9.2) 0.682
VKA n (%) 7 (6.9) 9 (18.4) 19 (10.3) 0.091
Antihypertensive drug n (%) 69 (67.6) 43 (87.8) 129 (70.1) 0.001

BMI Body Mass Index; HDL High density lipoprotein; LDL Low density lipoprotein; Lp (a) Lipoprotein (a); HbA1c Hemoglobin A1c; VKA Vitamin K antagonists.