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. Author manuscript; available in PMC: 2014 Apr 17.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Jun 20;33(8):1803–1811. doi: 10.1161/ATVBAHA.113.301857

Figure 2.

Figure 2

Intact cholesterol delivery from internalized LDL in BMP-enriched cells. Control and BMP-enriched cells were incubated with 50 μg/ml [3H]cholesteryloleate-LDL. (A) LDL uptake is expressed as nCi/mg cell protein. (B) CE hydrolysis is expressed as the percentage of [3H]cholesteryloleate converted to [3H]cholesterol in presence of the ACAT inhibitor F1394. (C) Control and BMP-enriched cells were incubated with [3H]cholesterol-LDL or [3H]cholesterol in absence or presence of 100 μg/ml LDL for 12h. Cholesterol esterification was measured as the proportion of radioactivity recovered in CE. (D) Control and BMP-enriched cells were incubated in absence (unloaded) or presence (loaded) of 100 μg/ml LDL for 12h. Sterol contents are expressed as nmol/mg cell protein. Data are the mean ± SD of 4 wells and representative of two independent experiments.