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. Author manuscript; available in PMC: 2014 Apr 17.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Jun 20;33(8):1803–1811. doi: 10.1161/ATVBAHA.113.301857

Figure 3.

Figure 3

LDL-derived cholesterol redistribution in BMP-enriched cells. (A) Control and BMP-enriched cells were incubated with 50μg/ml of [3H]cholesteryloleate-LDL for 12h. Cholesterol efflux was then stimulated by incubation with 10 mM MβCD for indicated times. (B, C) Control, BMP-enriched cells or U18666A-treated cells were incubated in absence or presence of 100μg/ml LDL for 12h. Cells were analyzed for SREBP2 (B) and HMG-CoA reductase (C) mRNA content as described in Materials and Methods. Data are the mean ± SD of 4–6 wells and representative of three independent experiments.

A, B, C, D, E, significantly different groups (multiple means comparisons by ANOVA and Tukey-Kramer method with α = 0.05).*p<0.05 compared to control by t-test.