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. 2014 Apr 16;9(4):e94789. doi: 10.1371/journal.pone.0094789

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Lysozyme fibers aggregate by lateral association to form bundles. Left, center: Arrows identify points at which two fibers join to form a bundle. Appearance of the bundle suggests the fibers wrap around each other in a spiral fashion, a process described by Terech [8] as helix formation. This requires the fibers be free to rotate. Right: Lysozyme fibers in a bundle may remain separated over a short distance and then rejoin, suggesting fiber helices must be aligned for bundling to occur.