Table 1. Characteristics of the 21 studies included in the meta-analysis of HIV and/or AIDS and the risk of melanoma.

Study	Location	Study period	Cohort description	Cohort size	Cases	Male %	Cohort median age at recruitment	Age range	Effect estimates providedb
									Pre-HAART	Post-HAART	AIDS
Cohort studies
Calabresi et al., 2013 [39]	Italy, 1 province	1999–2009	HIV or AIDS	5,090	8	82	35	19–64		SIR
Vogel et al., 2011 [35]	Germany, Bonn	1996–2009	HIV or AIDS	1,476	1	81	NS	16–85		SIR
Seaberg et al., 2010 [37]	United States, 4 metropolitan areas	1984–2007	HIV	6,949	9	100	32.6	<30–>50		SIR
Franceschi et al., 2010 [34]	Switzerland, 9 cancer registries	1985–2007	HIV or AIDS	9,429	11	81	32	>16	SIR	SIR
Powles et al., 2009 [33]	England, 1 clinical centre	1996–2007	HIV	11,112	5	90	NS	NS		SIR
Long et al., 2008 [2]	United States, 1 clinical centre	1996–2005	HIV	2,566	4	68	38	<30-> = 50		SIR
Patel et al., 2008 [30]	United States, 13 cancer registries	1992–2003	HIV	54,780	NS	76	NS	13–84
Serraino et al., 2007 [29]	Italy, 19 clinical centres France, 1 region	1988–2004	HIV	8074	2	81	31.3	<35->50
Hessol et al., 2004 [25]	United States	1994–1995	HIV or AIDS	1,554	2	0	NS	<30-50+
Herida et al., 2003 [24]	France, 12 cancer	1992–1999	HIV	77,025	19	84	Pre-HAART	15-69	SIR	SIR
	registries						39 (male); 33 (female)
							Post-HAART
							42(male); 38 (female)
Record linkage studies
Silverberg et al., 2011 [38]	United States, 1 state	1996–2008	HIV or AIDS	20,775	34	91	40.6	NS		RR
Simard et al., 2010 [36]	United States, 15 regions	1980–2004	AIDS	263,254	96	80	36	15-> = 50		SIR	SIR
Bedimo et al., 2009 [40]	United States	1997–2004	HIV or AIDS	33,420	96	98	NS	NS		IRR
Dal Maso et al., 2009 [31]	Italy, 24 cancer registries	1986–2005	HIVa or AIDS	21,951	6		Pre-HAART 32	16–69	SIR	SIR
							Post-HAART 38
Van Leeuwen et al., 2009 [32]	Australia, national	1982–2004	HIV or AIDS	17,175	53	92	NS	16–80	SIR	SIR
Hessol et al., 2007 [28]	United States, San Francisco	1990–2000	HIVa or AIDS	14,210	36	96	NS	16–86
Engels et al., 2006 [27]	United States, 6 states and	1980–2002	AIDS	375,933	45	89	Pre-HAART 37.7	>15	SIR	SIR	SIR
	5 cities						Post-HAART 39.3
Newnham et al., 2005 [26]	England	1985–2001	HIV or AIDS	33,190 HIV 12,126 AIDS	2	79 HIV 88 AIDS	NS	15–60			SIR
Frisch et al., 2001 [22]	United States, 11 regions	1978–1996	HIVa or AIDS	302,834	145		37 (male) 35 (female)	15–69	SIR		SIR
Gallagher et al., 2001 [23]	United States, New York State	1981–1994	HIVa or AIDS	122,993	24	89	NS	15–69	SIR
Cooksley et al., 1999 [21]	United States, single county	1985–1994	HIV or AIDS	14,986	6	85	35	<1–91	SIR

^aHIV described if cohort entry was AIDS defined but person-year calculations included pre AIDS onset.

^bCompared with the general population.