. Author manuscript; available in PMC: 2015 Apr 1.

Published in final edited form as: Heart Rhythm. 2014 Jan 17;11(4):646–652. doi: 10.1016/j.hrthm.2014.01.015

Table 2.

Genetic Association of CASQ2 SNPs with SCA and with CHF status

rsID	MAF	Allele^*	Call Rate	SCA		CHF
rsID	MAF	Allele^*	Call Rate	OR_adj (95% CI)^S	P	OR_adj (95% CI)^C	P
rs7521023	0.363	A>G	98.6	2.7 (1.44–5.13)^D	0.002	0.4 (0.25–0.76)^D	0.003
rs17034260	0.382	C>T	99.8	0.5 (0.29–0.94)^D	0.030	1.3 (0.85–1.86)^A	0.245
rs3811003	0.311	G>A	99.8	0.8 (0.52–1.27)^A	0.360	2.7 (1.16–6.34)^R	0.022
rs6684209¹	0.181	C>T	100.0	0.8 (0.44–1.28)^A	0.299	19.8 (3.63–108.2)^R,^C	<0.001
rs10923239¹	0.215	A>T	99.5	0.8 (0.49–1.37)^A	0.458	11.1 (2.39–50.9)^R	0.002
rs6665970¹	0.419	G>A	98.8	1.4 (0.92–2.13)^A	0.112	0.53 (0.30–0.95)^D	0.031
rs35672929¹	0.232	T>G	99.3	0.7 (0.41–1.15)^A	0.155	1.13 (0.73–4.41)^A	0.577
rs6677074¹	0.465	C>A	100.0	0.5 (0.23–0.98)^R	0.045	1.90 (1.01–4.47)^R	0.045
rs9428211	0.460	C>T	97.7	0.5 (0.23–1.01)^R	0.052	1.23 (0.84–1.85)^A	0.288
rs10754356	0.313	A>G	99.1	0.7 (0.47–1.14)^A	0.163	1.23 (0.82–1.86)^A	0.315
rs10923418²	0.428	G>A	100.0	0.5 (0.22–1.06)^R	0.071	1.08 (0.74–1.59)^A	0.684
rs9428090²	0.459	G>A	99.5	2.3 (1.15–4.40)^D	0.018	0.88 (0.60–1.30)^A	0.515
rs4074536	0.317	T>C	99.5	0.9 (0.59–1.35)^A	0.587	1.10 (0.74–1.62)^A	0.642

Abbreviations: 95% CI = 95% confidence interval; MAF = minor allele frequency; OR_adj = covariate-adjusted odds ratio; P = p-value; rsID = reference sequence IDentifier.

The alleles for each SNP are listed as follows: common > rare.

SNPs in haploblock 1

SNPs in haploblock 2

An additive genetic model fit the data best.

A dominant genetic model fit the data best.

A recessive genetic model fit the data best.

SNP is associated with SCA after adjustment for age, CHF status.

SNP is associated with CHF status after adjustment for age, gender, hypertension SCA.