Table I. Risk factors for developing FSE compared with simple FS.
Factor | FSE N (%) | Simple FS N (%) | Univariate OR (95% CI) | Multivariate OR (95% CI) |
---|---|---|---|---|
Age | ||||
<18 mo | 107 (63.3%) | 40 (39.2%) | 2.7 (1.6, 4.4) | 2.8 (1.47, 5.43) |
≥18 mo | 62 (36.7%) | 62 (60.8%) | 1.0 (Referent) | 1.0 (Referent) |
Daycare attendance | ||||
Daycare | 32 (19.5%) | 15 (15.3%) | 1.3 (0.7, 2.6) | |
No daycare | 132 (80.5%) | 83 (84.7%) | 1.0 (Referent) | |
Drinking during pregnancy | ||||
At least 1 drink in pregnancy | 10 (6.3%) | 1 (1.0%) | 6.5 (0.8, 51.7) | |
No drink in pregnancy | 149 (93.7%) | 97 (99.0%) | 1.0 (Referent) | |
First-degree family history of FS | ||||
Positive family history | 42 (25.0%) | 20 (20.2%) | 1.3 (0.7, 2.4) | 3.0 (1.28, 6.88) |
No family history | 126 (75.0%) | 79 (79.8%) | 1.0 (Referent) | 1.0 (Referent) |
First-degree family history of epilepsy | ||||
Positive family history | 22 (13.1%) | 8 (8.1%) | 1.7 (0.7, 4.0) | |
No family history Cpv | 146 (86.9%) | 91 (91.9%) | 1.0 (Referent) | |
Sex | ||||
Female | 87 (51.5%) | 43 (42.2%) | 1.5 (0.9, 2.4) | 2.2 (1.14, 4.43) |
Male | 82 (48.5%) | 59 (57.8%) | 1.0 (Referent) | 1.0 (Referent) |
Premature birth | ||||
≤ 37 wk | 46 (29.1%) | 15 (15.5%) | 2.2 (1.2, 4.3) | 1.8 (0.82, 3.90) |
>37 wk | 112 (70.9%) | 82 (84.5%) | 1.0 (Referent) | 1.0 (Referent) |
Smoking during pregnancy | ||||
No | 139 (82.2%) | 94 (94.0%) | 1.0 (Referent) | 1.0 (Referent) |
Yes | 30 (17.8%) | 6 (6.0%) | 3.4 (1.4, 8.4) | 2.4 (0.77, 7.77) |
Any temporal lobe abnormality other than increased T2 signal | ||||
Abnormal | 21 (13.0%) | 3 (3.1%) | 4.6 (1.3,16.0) | 4.6 (1.17,18.33) |
No abnormality | 140 (87.0%) | 93 (96.9%) | 1.0 (Referent) | 1.0 (Referent) |
Any structural abnormality on MRI | ||||
Abnormal | 60 (37.3%) | 34 (35.4%) | 1.1 (0.6, 1.8) | |
No abnormality | 101 (62.7%) | 62 (64.6%) | 1.0 (Referent) | |
Temperature | ||||
<104.0°F | 136 (81.0%) | 57 (55.9%) | 3.4 (1.9, 5.8) | 3.7 (1.80, 7.50) |
≥104.0°F | 32 (19.0%) | 45 (44.1%) | 1.0 (Referent) | 1.0 (Referent) |
Time temperature was recognized before seizure | ||||
1-24 h | 139 (82.2%) | 53 (53.0%) | 2.2 (1.2, 4.2) | 2.4 (1.10, 5.33) |
<1 h | 28 (16.6%) | 24 (24.0%) | 1.0 (Referent) | 1.0 (Referent) |
>24 h | 2 (1.2%) | 23 (23.0%) | 0.1 (0.0, 0.3) | 0.1 (0.01,0.56) |