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. Author manuscript; available in PMC: 2014 Apr 16.
Published in final edited form as: J Pediatr. 2013 Jul 1;163(4):1147–51.e1. doi: 10.1016/j.jpeds.2013.05.038

Table II. Risk factors for developing FSE compared with complex FS.

Factor FSE
N (%)
Complex
FS N (%)
Univariate
OR
(95% CI)
Multivariate
OR
(95% CI)
Age
 <18 mo 107 (63.31%) 27 (60.00%) 1.15 (0.6,2.3)
 ≥18 mo 62 (36.69%) 18 (40.00%) 1.0 (Referent)
Daycare attendance
 Daycare 32 (19.51%) 3 (6.82%) 3.31 (1.0,11.4) 3.0 (0.7,13.4)
 No daycare 132 (80.49%) 41 (93.18%) 1.0 (Referent) 1.0 (Referent)
Drinking during pregnancy
 At least 1 drink in pregnancy 10 (6.29%) 0 (0%) NA
 No drink in pregnancy 149 (93.71%) 45 (100.00%) 1.0 (Referent)
First-degree family history of FS
 Positive family history 42 (25.00%) 9 (20.00%) 1.33 (0.6,3.0)
 No family history 126 (75.00%) 36 (80.00%) 1.0 (Referent)
First-degree family history of epilepsy
 Positive family history 22 (13.10%) 1 (2.22%) 6.63 (0.9,50.6)
 No family history Cpv 146 (86.90%) 44 (97.78%) 1.0 (Referent)
Sex
 Female 87 (51.48%) 22 (48.89%) 1.11 (0.6,2.1)
 Male 82 (48.52%) 23 (51.11%) 1.0 (Referent)
Premature birth
 ≤ 37 wk 46 (29.11%) 8 (17.78%) 1.90 (0.8,4.4)
 >37 wk 112 (70.89%) 37 (82.22%) 1.0 (Referent)
Smoking during pregnancy
 No 139 (82.25%) 38 (84.44%) 1.0 (Referent)
 Yes 30 (17.75%) 7 (15.56%) 1.17 (0.5,2.9)
Any temporal lobe abnormality other
  than increased T2 signal
 Abnormal 21 (13.04%) 5 (12.82%) 1.02 (0.4, 2.9)
 No abnormality 140 (86.96%) 34 (87.18%) 1.0 (Referent)
Any structural abnormality on MRI
 Abnormal 60 (37.27%) 16 (41.03%) 0.85 (0.4,1.7) 1.3 (0.5, 3.1)
 No abnormality 101 (62.73%) 23 (58.97%) 1.0 (Referent) 1.0 (Referent)
Temperature
 <104.0°F 136 (80.95%) 27 (60.00%) 2.83 (1.4, 5.8) 3.6 (1.5, 8.5)
 ≥104.0°F 32 (19.05%) 18 (40.00%) 1.0 (Referent) 1.0 (Referent)
Time temperature was recognized before seizure
 1-24 h 139 (82.25%) 21 (46.67%) 3.07 (1.4, 6.9) 3.4 (1.4, 8.4)
 <1 h 28 (16.57%) 13 (28.89%) 1.0 (Referent) 1.0 (Referent)
 >24 h 2 (1.18%) 11 (24.44%) 0.08 (0.0, 0.4) 0.1 (0.0, 0.5)