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. Author manuscript; available in PMC: 2014 Apr 16.
Published in final edited form as: J Pediatr. 2013 Jul 1;163(4):1147–51.e1. doi: 10.1016/j.jpeds.2013.05.038

Table III. Risk factors for developing complex FS compared with simple FS.

Factor Complex
FS N (%)
Simple
FS N (%)
Univariate
OR (95% CI)
Age
 <18 mo 27 (60.0%) 40 (39.2%) 2.3 (1.1,4.8)
 ≥18 mo 18 (40.0%) 62 (60.8%) 1.0 (Referent)
Daycare attendance
 Daycare 3 (6.8%) 15 (15.3%) 0.4 (0.1,1.5)
 No daycare 41 (93.2%) 83 (84.7%) 1.0 (Referent)
Drinking during pregnancy
 At least 1 drink in pregnancy 0 (0%) 1 (1.0%) NA
 No drink in pregnancy 45 (100.0%) 97 (99.0%) 1.0 (Referent)
First-degree family history of FS
 Positive family history 9 (20.0%) 20 (20.2%) 1.0 (0.4, 2.4)
 No family history 36 (80.0%) 79 (79.8%) 1.0 (Referent)
First-degree family history of epilepsy
 Positive family history 1 (2.2%) 8 (8.1%) 0.3 (0.0, 2.1)
 No family history 44 (97.8%) 91 (91.9%) 1.0 (Referent)
Sex
 Female 22 (48.9%) 43 (42.2%) 1.3 (0.6, 2.7)
 Male 23 (51.1%) 59 (57.8%) 1.0 (Referent)
Premature birth
 ≤ 37 wk 8 (17.8%) 15 (15.5%) 1.2 (0.5, 3.0)
 >37 wk 37 (82.2%) 82 (84.5%) 1.0 (Referent)
Smoking during pregnancy
 No 38 (84.4%) 94 (94.0%) 1.0 (Referent)
 Yes 7 (15.6%) 6 (6.0%) 2.9 (0.9, 9.1)
Any temporal lobe abnormality
  other than increased T2 signal
 Abnormal 2 (5.1%) 1 (1.0%) 5.1 (0.5, 58.3)
 No abnormality 37 (94.9%) 95 (99.0%) 1.0 (Referent)
Any structural abnormality on MRI
 Abnormal 16 (41.0%) 34 (35.4%) 1.3 (0.6, 2.7)
 No abnormality 23 (59.0%) 62 (64.6%) 1.0 (Referent)
Temperature
 <104.0°F 27 (60.0%) 57 (55.9%) 1.2 (0.6, 2.4)
 ≥ 104.0°F 18 (40.0%) 45 (44.1%) 1.0 (Referent)
Time temperature was
  recognized before seizure
 1-24 h 21 (46.7%) 53 (53.0%) 0.7 (0.3,1.7)
 <1 h 13 (28.9%) 24 (24.0%) 1.0 (Referent)
 >24 h 11 (24.4%) 23 (23.0%) 0.9 (0.3, 2.4)