Table 1.

CaM-binding affinities of peptides derived from different subfamilies of connexins.

Peptide	Family	Position	Predicted Scorea	Helicityb	Kd (nM)		Reference
					Ca2+	EGTA
hCx43p138–157	α	CL	16	55.6	860	nd	[48]
shCx44p129–150	α	CL	6	59.5	49	>5000	[50]
hCx50p141–166	α	CL	13	95.3	4.9	>8000	[52]
hCx32p1–21	β	NT	9	nd	27	nd	[60]
rCx32p216–230	β	CT	0	nd	2100	nd	[60]
mCx36p269–321	γ	CT	14	nd	11	nd	[55]

^aPredicted by CaM Target Database

^bPeptide helicity induced by 90% TFE