TABLE 1.

MEAN (±S.D.) DEMOGRAPHIC & FUNCTIONAL MEASURES FOR AMYOTROPHIC LATERAL SCLEROSIS (ALS), FOUR-REPEAT TAUOPATHIES (4R-TAU), AND HEALTHY SENIORS

FUNCTIONAL MEASURE	ALS (N=51)	4R-TAU (N=23)	HEALTHY SENIORS (N=23)
Age	54.88 (10.6)	65.4 (9.4)*	59.9 (6.0)
Education	14.86 (3.9)	14.55 (3.4)	15.9 (4.3)
Gender (M / F)	35 / 16	14 / 9	12 / 11
MMSE (adjusted)	27.53 (3.3)	24.45 (5.13)^#	29.39 (0.7)
Disease Duration (months)	24.72 (14.1)	54.87 (23.4)*	--
ALSFRS-R (n=42)	37.74 (7.9)	--	--
Progression Rate (n=42)	0.46 (0.4)	--	--

NOTE:

^*4R-TAU differs significantly from ALS at p<0.001;

^{^}4R-TAU differs significantly from ALS at p<0.01;

^#4R-TAU differs significantly from healthy seniors at p<0.001.