Table 1.
Demographic, Dietary and Laboratory Characteristics of Subjects
| Variable | Aromatase Inhibitor Study22 |
Proton Pump Inhibitor Study21 |
Vitamin D Study20 |
All Studies |
|---|---|---|---|---|
| Number of Subjects† | n=10 | n=21 | n=19† | n=50 |
| Studies per Subject | 2 | 3 | 2 | |
| Age, years | 66 ± 7 | 58 ± 7 | 58 ± 8 | 60 ± 8 |
| Race | 9 White 1 Black |
17 White 2 Black 2 Hispanic |
17 White 1 Black 1 Indian |
43 White 4 Black 2 Hispanic 1 Indian |
| Body Mass Index, kg/m2 | 29 ± 4 | 29 ± 5 | 29 ± 5 | 29 ± 5 |
| Fractional Calcium Absorption | 0.155 ± 0.042 | 0.204 ± 0.097 | 0.243 ± 0.070 | 0.209 ± 0.084 |
| Net Calcium Absorption | 251 ± 88 | 257 ± 127 | 212 ± 74 | 239 ± 102 |
| Kilocalories, day | 1923 ± 418 | 2195 ± 337 | 1660 ± 368 | 1826 ± 409 |
| Protein, g/day | 86 ± 20 | 88 ± 21 | 73 ± 17 | 79 ± 20 |
| Fat, g/day | 84 ± 31 | 87 ± 22 | 66 ± 27 | 74 ± 26 |
| Carbohydrates, g/day | 219 ± 60 | 265 ± 58 | 192 ± 77 | 220 ± 60 |
| Fiber, g/day | 20 ± 5 | 24 ± 11 | 16 ± 7 | 20 ± 9 |
| Dietary Calcium, mg/day | 994 ± 372 | 998 ± 330 | 832 ± 215 | 940 ± 304 |
| Calcium supplement, | 720 ± 530 | 403 ± 568 | 85 ± 170 | 358 ± 512 |
| All Calcium Intake, mg/day | 1714 ± 640 | 1410 ± 648 | 912 ± 287 | 1281 ± 612 |
| Iron, mg/day | 12 ± 3 | 16 ± 5 | 12 ± 3 | 13 ± 5 |
| Magnesium, mg/day | 378 ± 100 | 364 ± 110 | 260 ± 66 | 320 ± 110 |
| Oxalate, servings/day | 1.5 ± 1.0 | 1.2 ± 1.0 | 0.7 ± 0.6 | 0.9 ± 0.8 |
| Phosphorus, mg/day | 1378 ± 490 | 1521 ± 409 | 1252 ± 318 | 1388 ± 405 |
| Potassium, mg/day | 3062 ± 971 | 3318 ± 829 | 2613 ± 692 | 2993 ± 855 |
| Vitamin D, IU/day | 217 ± 111 | 151 ± 96 | 107 ± 84 | 146 ± 102 |
| Serum Calcium, mg/dL | 9.3 ± 0.5 | 9.1 ± 0.4 | 9.3 ± 0.3 | 9.2 ± 0.4 |
| Serum Creatinine, mg/dL | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 |
| GFR, mL/minute | 77 ± 11 | 86 ± 19 | 80 ± 17 | 83 ± 18 |
| PTH, pg/dL | 48 ± 25 | 49 ± 24 | 53 ± 15 | 50 ± 21 |
| 25(OH)D, ng/mL | 40 ± 7 | 28 ± 13 | 22 ± 4 | 28 ± 11 |
| 1,25(OH)2D, pg/mL | 44 ± 17 | 47 ± 26 | 37 ± 12 | 43 ± 20 |
The table summarizes the baseline data of all subjects, including habitual intake of nutrients based on analysis of four to seven day food diaries. Data exhibited a normal or approximately normal distribution, and are summarized using the mean and standard deviation for each study and for all studies.
†
Data include the baseline visit of one subject whose urine sample from one study visit was mishandled; therefore her paired calcium absorption data were not reported in the original study.