Skip to main content
. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Eur J Pain. 2013 Oct 23;18(5):649–658. doi: 10.1002/j.1532-2149.2013.00416.x

Figure 1. Unilateral L4 SNL injury caused nociceptions that correlated with α2δ1 upregulation in dorsal spinal cord and DRG.

Figure 1

Responses to noxious cold (A), and paw withdrawal latency (PWL) to heat (B) stimuli in the hindpaws of injury-side from sham and SNL mice were tested blindly at designated time points post surgery. Data presented are the means ± SEM from the number of animals indicated. **p < 0.01 compared with control values by one-way ANOVA test. The α2δ1 levels in injury-side of dorsal spinal cord and DRG were examined one-week post sham or SNL surgery with Western blots (C). β-actin was used as loading control as described in the Method. Representative Western blots were shown on top of each corresponding bar graph presented as the means ± SEM from 8 each of sham and SNL mice in 3 independent Western blots. *p < 0.05, **p < 0.01, compared with control values by Student's t test.