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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Brain Behav Immun. 2014 Feb 10;0:192–201. doi: 10.1016/j.bbi.2014.02.001

Figure 1. Basal behavioral assessments.

Figure 1

A) Rag2−/− mice exhibit significantly greater locomotor activity than WT mice with comparable habituation to the arena in the OFT (2-way repeated measures ANOVA: immune status: p = 0.046; time: p < 0.0001; interaction: ns). B) Rag2−/− mice spend significantly more time in the center of the arena during the first ten minutes of the OFT session (immune status × time: p = 0.011; Fisher’s LSD post hoc). C) No significant differences were found in either the time spent in the open arms or total distance traveled in the EPM. D) There are no evident differences in olfaction between WT and Rag2−/− mice as determined by the latency to retrieve buried food. * p < 0.05, ns: non-significant