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. Author manuscript; available in PMC: 2015 Apr 15.
Published in final edited form as: Clin Cancer Res. 2014 Feb 13;20(8):2115–2125. doi: 10.1158/1078-0432.CCR-13-2221

FIGURE 5. RET Expression is Associated with ERα Positive Breast Cancers.

FIGURE 5

A. RNA extracted from primary human breast cancers and patient matched normal breast tissue demonstrates significantly higher mean RET expression in ERα-positive tumors compared to ERα-negative tumors and normal breast tissue. The data represent values from 20 ERα-positive, 10 ERα-negative tumors, and the 30 samples of matched normal breast tissue, which are overlaid for some data points. The p values were calculated using the Student’s t-test. B. When a cutoff of 0.5 fold RET expression relative to MCF-7 is used, significantly more ERα-positive tumors are RET positive compared to ERα-negative and normal breast tissue, p=0.001. The p value was calculated using the analysis of variation (ANOVA).