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Immunohistochemical staining for phosphorylated and total FAK in pediatric renal tumor specimens.
| Tumor Type | n | FAK 4.47 (%) | pFAK Y397 (%) | P Value (vs. MRKT) |
|---|---|---|---|---|
| Malignant Rhabdoid Kidney Tumor | 12 | 9 (75) | 6 (50) | - |
| Clear Cell Sarcoma | 12 | 4 (33) | 1 (8) | NS |
| Wilms Tumor | 19 | 6 (32) | 4 (21) | 0.03 |
| Mesoblastic Nephroma | 12 | 1 (8) | 0 (0) | 0.003 |
FAK 4.47 = total FAK protein; pFAK Y397 = FAK phosphorylated at tyrosine 397 residue
