CFD simulation results of the cross-sectional flow distribution at the end of the curved channel without optimization of fluid rates for curvature angles of (a) 90°, (b) 135°, and (c) 180°. CFD simulation results of the cross-sectional flow distribution with an optimized rate of vertical sheath flow for curvature angles of (d) 90°, (e) 135°, and (f) 180°. In each image, the inset at the bottom right corner indicates the enlarged focal point of the sample flow.