Table 2.

Body mass, soleus muscle mass, and muscle mass-to-body mass ratio for weight-bearing and unloaded groups transfected with either wild-type or mutant MuRF1 promoter plasmids

Constructs	Weight Bearing	Hindlimb Unloaded	P Value
Body mass, g
MuRF1 (WT)	185.6 ± 5.38	190.9 ± 3.09	NS
allkBmut MuRF1	185.9 ± 4.34	184.3 ± 4.34	NS
allFoxomut MuRF1	174.8 ± 4.16	160.8 ± 1.04	NS
kB1mut MuRF1	196.0 ± 2.04	186.9 ± 2.10	NS
kB2mut MuRF1	194.4 ± 2.13	190.2 ± 2.11	NS
kB3mut MuRF1	193.0 ± 6.49	193.2 ± 3.24	NS
Muscle mass, mg
MuRF1 (WT)	108.4 ± 3.11	80.2 ± 1.98	<0.001
allkBmut MuRF1	115.4 ± 2.29	85.2 ± 4.22	<0.001
allFoxomut MuRF1	93.8 ± 4.00	69.6 ± 3.09	<0.001
kB1mut MuRF1	106.2 ± 1.58	73.1 ± 1.87	<0.001
kB2mut MuRF1	107.5 ± 4.70	70.9 ± 2.12	<0.001
kB3mut MuRF1	110.7 ± 1.97	80.1 ± 2.35	<0.001
Muscle mass/body mass, mg/g
MuRF1 (WT)	0.594 ± 0.026	0.420 ± 0.012	<0.001
allkBmut MuRF1	0.623 ± 0.027	0.462 ± 0.022	<0.01
allFoxomut MuRF1	0.536 ± 0.011	0.433 ± 0.019	<0.01
kB1mut MuRF1	0.542 ± 0.008	0.391 ± 0.008	<0.001
kB2mut MuRF1	0.553 ± 0.022	0.373 ± 0.011	<0.001
kB3mut MuRF1	0.573 ± 0.035	0.414 ± 0.012	<0.001

Values are means ± SE.

WT, wild type.