Table 4.
Gene Name | Gene | Induced by Cold in BAT | Gene Function |
---|---|---|---|
4921536K21Rik | RIKEN cDNA 4921536K21 gene | Yes | |
9030619P08Rik | RIKEN cDNA 9030619P08 gene | Yes | |
9430098F02Rik | RIKEN cDNA 9430098F02 gene | Yes | |
Abca6 | ATP-binding cassette, sub-family A (ABC1), member 6 | ||
Abhd1 | Abhydrolase domain containing 1 | Yes | |
Acaa1b | Acetyl-Coenzyme A acyltransferase 1B | Yes | |
Acoxl | Acyl-coenzyme A oxidase-like | ||
Adrm1 | Adhesion regulating molecule 1 | Yes | |
Apoc2 | Apolipoprotein C-II | Yes | Extracellular |
Apoc4 | Apolipoprotein C-IV | Extracellular | |
Apold1 | Apolipoprotein L domain-containing 1 | Yes | |
Aqp11 | Aquaporin 11 | Yes | Plasma membrane |
Atrn | Attractin | Yes | Plasma membrane, |
C2cd2l | C2 calcium-dependent domain containing 2-like | Yes | |
Catsper3 | Cation channel, sperm associated 3 | Plasma membrane | |
Ccny | Cyclin Y | Yes | |
Chrna2 | Cholinergic receptor, nicotinic, alpha polypeptide 2 | Yes | Plasma membrane |
Cir1 | Corepressor interacting with RBPJ, 1 | ||
Cldn22 | Claudin 22 | Plasma membrane | |
Cmbl | Carboxymethylenebutenolidase-like (Pseudomonas) | ||
Crtac1 | Cartilage acidic protein 1 | Extracellular | |
Cyp4a10 | Cytochrome P450, family 4, subfamily a, polypeptide 10 | Yes | |
Dbp | D site albumin promoter binding protein | Yes | Transcription factor |
Dcst1 | DC-STAMP domain containing 1 | ||
Drd1a | Dopamine receptor D1A | Yes | Signaling Molecule |
Fabp12 | Fatty acid-binding protein 12 | Yes | |
Fndc8 | Fibronectin type III domain containing 8 | Yes | |
Gys2 | Glycogen synthase 2 | Yes | |
Katna1 | Katanin p60 (ATPase-containing) subunit A1 | Yes | Cell Cycle |
Klhl2 | Kelch-like 2, Mayven (Drosophila) | ||
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | Yes | Signaling Apoptosis |
Lipf | Lipase, gastric | Extracellular | |
Lsm1 | LSM1 homolog, U6 small nuclear RNA associated | Yes | |
Mfsd3 | Major facilitator superfamily domain containing 3 | Yes | |
Mpv17l | Mpv17 transgene, kidney disease mutant-like | Yes | |
Nploc4 | Nuclear protein localization 4 homolog (S. cerevisiae) | Yes | |
Nxnl1 | Nucleoredoxin-like 1 | Yes | |
Padi3 | Peptidyl arginine deiminase, type III | ||
Pex16 | Peroxisomal biogenesis factor 16 | Yes | |
Pla2 g2e | Phospholipase A2, group IIE | Yes | Extracellular |
Psmd4 | Proteasome (prosome, macropain) 26S subunit, nonATPase | Yes | |
Rcl1 | RNA terminal phosphate cyclase-like 1 | ||
Reep6 | Receptor accessory protein 6 | Yes | |
Rnf146 | ring finger protein 146 | Yes | |
Rora | RAR-related orphan receptor alpha | Yes | Transcription factor |
Slc9a6 | Solute carrier family 9 member 6 | Yes | |
Sphk2 | Sphingosine kinase 2 | Yes | Signaling molecule |
Tbata | Thymus, brain and testes associated | ||
Tinag | Tubulointerstitial nephritis antigen | Yes | |
Tmem120a | Transmembrane protein 120A | Yes | |
Trfr2 | Transferrin receptor 2 | Yes | Plasma membrane |
Vmn2r1 | Vomeronasal 2, receptor 2 | Yes | |
Zwint | ZW10 interactor | Yes | Cell cycle |
Boldface indicates genes that are within the top 200 most significantly upregulated genes in 6°C versus 28°C subcutaneous WAT.