Table 1.

Doppler echocardiographic measurements

	Sham, wk			Dual Transgenic, wk
Parameters	0	4	8	0	4	8
n	16	16	13	8	8	5
Heart rate, beats/min	344.3 ± 8.2	367.1 ± 14.8	369.3 ± 12.3	311.5 ± 15.3	336.0 ± 12.8	367.4 ± 28.6
Ejection time, ms	54.2 ± 3.1	56.4 ± 3.5	48.8 ± 1.7	56.3 ± 2.4	51.3 ± 1.6	49.3 ± 4.7
Isovolumetric relaxation time, ms	29.2 ± 1.0	26.3 ± 1.6	25.8 ± 0.4	31.9 ± 3.7	26.0 ± 1.2	21.2 ± 1.6*
Isovolumetric contraction time, ms	26.8 ± 1.2	26.3 ± 1.4	23.9 ± 1.0	30.2 ± 1.7	30.3 ± 1.9	19.4 ± 3.9*

Values are means ± SE.

^*Comparison vs. 0 wk dual transgenic, P < 0.05.