Table 1.
Control | Shunt Open | Shunt Closed | P Value (Shunt Open vs. Control) | P Value (Shunt Closed vs. Control) | |
---|---|---|---|---|---|
SBP, mmHg | 66.3 ± 2.1 | 55.7 ± 3.5 | 72.8 ± 7.7 | 0.02* | 0.40 |
DBP, mmHg | 54.6 ± 2.4 | 29.0 ± 2.1 | 58.3 ± 8.4 | <0.001* | 0.65 |
LPBF, L/min | 0.50 ± 0.06 | 2.12 ± 0.21 | 0.96 ± 0.16 | <0.001* | 0.02* |
PAP, mmHg | 11.8 ± 0.8 | 23.7 ± 2.4 | 15.7 ± 2.6 | <0.001* | 0.16 |
LAP, mmHg | 4.9 ± 0.64 | 11.2 ± 1.7 | 4.7 ± 1.0 | <0.01* | 0.81 |
RAP, mmHg | 2.9 ± 0.6 | 3.2 ± 0.6 | 2.2 ± 0.4 | 0.82 | 0.37 |
HR, beats/min | 133.7 ± 4.3 | 136.7 ± 6.2 | 130.8 ± 7.3 | 0.70 | 0.73 |
Values are expressed as means ± SE of mean; n = 6 in each group.
SBP, systolic blood pressure; DBP, diastolic blood pressure; LPBF, left pulmonary blood flow; PAP, pulmonary artery pressure; LAP, left atrial pressure; RAP, right atrial pressure; HR, heart rate.
Significant difference.