Table 4.
Accuracy evaluation of the associations between TCM herbs and genes.
| Herb/gene | Disease | Sample (number of related genes/herbs) | TP | Precision |
|---|---|---|---|---|
| Artemisia annua | Malaria | 50 | 40 | 80% |
| Artemisia annua | Breast Neoplasm | 9 | 9 | 100% |
| Aconitum carmichaelii | Hypertension | 50 | 38 | 76% |
| Aconitum carmichaelii | Arthritis | 13 | 10 | 76.92% |
| Ginkgo biloba | Alzheimer disease | 50 | 43 | 86% |
| Ginkgo biloba | Atherosclerosis | 24 | 21 | 87.5% |
| Salvia miltiorrhiza | Asthma | 50 | 43 | 86% |
| Salvia miltiorrhiza | Parkinson Disease | 50 | 37 | 74% |
| IL6 | Breast Neoplasm | 46 | 39 | 84.78% |
| IL6 | Prostatic Neoplasm | 22 | 19 | 86.36% |
| TNF | Asthma | 26 | 23 | 88.46% |
| TNF | Stomach Neoplasm | 16 | 15 | 93.75% |
| IFNG | Vascular Disease | 5 | 5 | 100% |
| IFNG | Tuberculosis | 11 | 11 | 100% |
| MMP9 | Alzheimer Disease | 23 | 18 | 78.26% |
| MMP9 | Diabetic Retinopathy | 2 | 2 | 100% |
|
| ||||
| Sum up | 447 | 373 | 83.45% | |