TABLE 2.
Summary of affected genes involved in phototransduction
Embryos injected with SCM or SULT4A1 MO were subjected to gene expression profiling using RNA-seq. P values were determined using analysis of variance.
| Protein | Gene | Fold Change | P value | Localization |
|---|---|---|---|---|
| Sulfotransferase family 4A member 1 | SULT4A1 | −2.15 | <0.0001 | |
| Rhodopsin | RHO | 1.17 | 0.8233 | Rod |
| G protein, α-transducing activity polypeptide 1 | GNAT1 | 2.09 | <0.0001 | Rod |
| G protein, α-transducing activity polypeptide 2 | GNAT2 | 3.35 | <0.0001 | Cone |
| G protein–coupled receptor kinase 7a | grk7a | 3.33 | <0.0001 | Cone |
| Opsin 1, long-wave-sensitive, 2 | OPN1LW2 | 2.31 | <0.0001 | Cone |
| Opsin 1, medium-wave-sensitive, 2 | OPN1MW1 | 4.56 | <0.0001 | Cone |
| Opsin 1, short-wave-sensitive, 1 | OPN1SW1 | 3.62 | <0.0001 | Cone |
| Opsin 1, short-wave-sensitive, 2 | OPN1SW2 | 3.29 | <0.0001 | Cone |
| G protein–coupled receptor kinase 1b | grk1b | 4.27 | <0.0001 | Cone |
| Arrestin 3, retinal | ARR3 | 1.87 | <0.0001 | Cone |
| Guanine nucleotide binding protein (G protein) γ-transducing activity polypeptide 2b | gngt2b | 3.24 | <0.0001 | Both |
| Phosducin b | pdcb | 2.76 | <0.0001 | Both |
| Guanylate cyclase activator 1e | guca1e | 4.39 | 0.00018 | Both |
| Cyclic nucleotide gated channel β 1a | cngb1a | 3.51 | <0.0001 | Both |