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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Biol Cell. 2014 Feb 25;106(4):126–138. doi: 10.1111/boc.201400003

Figure 1. Defects in Ub-H2B promote splicing defects.

Figure 1

(A) Schematic of probes contained on the microarray for each intron-containing gene. (B) Heat maps of log2 ratios of each gene feature in bre1Δ or htb1K123R compared to isogenic WT strains after a 3-hour shift to 39°C. Gene order is different for each sub-panel. (C) RT-qPCR measurements of unspliced mRNAs using single-locus RT-qPCR. Percent unspliced RNA is represented as fold change compared to wild-type.