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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Exp Dermatol. 2014 Mar;23(3):189–194. doi: 10.1111/exd.12346

Figure 3.

Figure 3

CD4 or CD8 lymphocyte deficiency changes the profiles of cytokine expression in the wounds. mRNA expression of cytokines was determined by real-time PCR. A) IL-1β, * p<0.05 compared to wild type; # p<0.001 compared to wild type and CD8 deficient mice. B) IL-6, #p<0.001 compared to wild type and CD8 deficient, *p<0.05 compared to CD8 deficient. C) IL-17 and D) IFN-γ, #p<0.01 compared to wild type and CD8 deficient. E) CXCL-1, # p<0.001 compared to wild type and CD8 deficient, * p<0.05 compared to CD8 deficient, **p<0.05 compared to wild type and CD4 deficient. F) TNF-α, # p<0.001 compared to wild type and CD4 deficient, * p<0.05 compared to wild type and CD4 deficient. G) CCL-2, * p<0.05 compared to wild type and CD4 deficient. H) TGF-β1. I) IL-4, *p<0.01 and **p<0.05 compared to wild type and CD4 deficient mice. #p<0.05 compared to CD4 deficient mice. J) IL-10, *p<0.05, #p<0.001 compared to CD4 or CD8 deficient; **p<0.05 compared to CD8 deficient. K) IL-13. N=3 in each group and each time point; a two-way ANOVA followed by a Tukey’s multiple comparisons test was used. Error bars = standard deviation.