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The absence of Panx1 prevents the increase in levels of thiobarbituric reactive substances in denervated skeletal muscles. Seven days after denervation gastrocnemius muscles were isolated from wild type (wt, white bar), or Panx1 deficient mice (Panx1−/−, black bar), and levels of thiobarbituric acid reactive substances (TBARS) were evaluated in denervated vs. not denervated muscles. *P < 0.05; ns, not significant.
