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Tree of regeneration; depicting the competence for regeneration across the kingdoms of life. Adult stem cells are partly differentiated cells that can give rise to a limited number of cell types while the pluripotent stem cells are competent to give rise to all lineages of cells. The pluripotent stem cells which play a major role in executing the regenerative duties in the lower organisms of each kingdom gave way to adult stem cells and occupy confined niches in higher organisms.
