Table 5. Antiemetics based on recommendations by the American College of Physicians.
Drug | Cause of nausea | Dose |
Prochlorperazine | Initiation of opioid therapy | 10 mg orally or 25 mg rectally, 2 or 3 times daily |
Haloperidol | Stimulation of chemoreceptor | 1.5–5 mg, orally 3–4 times daily; 2–10 mg |
Intramuscularly, 2 or 3 times daily | ||
Prochlorperazine | Trigger zone by chemotherapy | 10 mg orally or 25 mg rectally, 2 or 3 times daily |
Methotrimeprazine |
2–6.25 mg intramuscularly, 3 times daily; 6–25 mg, over 24 h |
|
Scopolamine (transdermal patch) | Vertigo | Apply 1 patch every 2–3 days |
Meclizine |
50 mg orally or 25–50 mg intramuscularly, 3 times daily |
|
Metoclopramide | Delayed gastric emptying | 10–20 mg, 2–3 times daily; 1–3 mg h intravenously |
Octreotide | Bowel obstruction | 50–100 lg subcutaneously 2 or 3 times daily or 300 lg |
During 24hours subcutaneously | ||
Ondansetron | Multiple causes, refractory | 4–8 mg orally, 2 or 3 times daily |
Dexamethasone | 2–4 mg orally, 2 or 3 times daily |