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Summary of histological analysis of the extent of optic fissure closure in Sall2−/− null and Sall2+/− mouse embryos
| Stage | Genotype | Anterior |
Midline |
Posterior |
Total eyes | |||
|---|---|---|---|---|---|---|---|---|
| Open | Closed | Open | Closed | Open | Closed | |||
| E13.5 | Sall2−/− | 12 (100%) | 0 (0%) | 6 (50%) | 6 (50%) | 0 (0%) | 12 (100%) | 12 |
| Sall2+/− | 0 (0%) | 5 (100%) | 0 (0%) | 5 (100%) | 0 (0%) | 5 (100%) | 5 | |
| E14.5 | Sall2−/− | 9 (100%) | 0 (0%) | 3 (33%) | 6 (67%) | 0 (0%) | 9 (100%) | 9 |
| Sall2+/− | 0 (0%) | 10 (100%) | 0 (0%) | 10 (100%) | 0 (0%) | 10 (100%) | 10 | |
