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. 2013 Dec 30;23(10):2651–2664. doi: 10.1093/hmg/ddt660

Figure 3.

Figure 3.

Effects of SAHA on adipogenesis of the epididymal fat of Thra1PV and Thra1PV/+Ncor1ΔID/ΔID mice. (A) Comparison of epididymal fat weights among adult mice (3–3.5 months old) with indicated genotypes with or without treatment of SAHA (3–3.5 months old; n = 8–13 mice per group). Ratios of fat mass versus body weight were determined. Data are expressed as mean values ± SEM with P-values shown. (B) Representative histological features of the epididymal fat of four different genotypes (Thra1+/+Ncor1+/+, Thra1+/+Ncor1ΔID/ΔID, Thra1PV/+Ncor1+/+ and Thra1PV/+Ncor1ΔID/ΔID) with or without SAHA treatment. (C) Adipocyte size was measured for each genotype shown in (B) using NIH IMAGE software (ImageJ) and plots were presented to reflect the size distribution (n = 8–9 mice per genotype).