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CRCs for celecoxib, zaprinast, sildenafil and rolipram. The study was performed on human mesenteric arteries (without endothelium) contracted by ET-1. Points marked on the CRC present the mean relaxation effect in % and SE (n=12 arteries per group). Graphs were approximated to the sigmoidal curve. CRCs, concentration response curves; ET-1, endothelium; SE, standard error.
