Table 2.

Tissue clearance rates for curcumin and MCC80

Group	Time (h)	Mass (nmol)	Mass (nmol/g tissue)	%ID (nmol/nmol)
Curcumin	0*	158	765	59
	2	98 ± 24	531 ± 81	36 ± 8.9
	48&	0.67 ± 0.004	7.2 ± 1.3	0.25 ± 0.002
	96	0.39 ± 0.12	2.8 ± 0.95	0.14 ± 0.04
MCC80	0*	90	1080	33
	2	33 ± 8.1	280 ± 73	12 ± 3.0
	48	3.5 ± 1.2	37 ± 10	1.3 ± 0.46
	96	2.2 ± 0.32	15 ± 2.1	0.80 ± 0.12

^*=0 h validations were conducted for n=1 animals per group and not included in statistical analyses.

^&All other time points represent n = 3 animals per group (mean ± SEM), except where outliers were removed due to injection error (n = 2). There were no statistical differences between curcumin or MCC80 (one-way ANOVA, p = 0.2).