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. Author manuscript; available in PMC: 2015 Apr 15.
Published in final edited form as: Dev Biol. 2014 Feb 22;388(2):149–158. doi: 10.1016/j.ydbio.2014.02.010

Figure 1. Postn-Cre mediated deletion of Hand2 from AV and OFT cushions.

Figure 1

Transverse section of Postn-Cre(+) lacZ stained control AV cushion at E12.5 (A). Hand2 ISH of control (B) and H2CKO (C) AV cushion. Transverse section of Postn-Cre(+) β-galactosidase stained control OFT cushions at E12.5 (D). Hand2 ISH of control (E) and H2CKO (F) OFT cushion. Black arrows indicate cushion mesenchyme, brown arrows indicate the primitive tricuspid valve (TV), mitral valve (MV), and pulmonary valve (PV). Asterisks indicate deletion of Hand2, right ventricle, RV; left ventricle, LV.