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. Author manuscript; available in PMC: 2015 Apr 15.
Published in final edited form as: Dev Biol. 2014 Feb 22;388(2):149–158. doi: 10.1016/j.ydbio.2014.02.010

Figure 6. Postn-Cre H2CKO pups have significantly slower heart rates and expanded Anf expression.

Figure 6

H2CKO pups that survive to P3 are noticeably smaller than littermates (A). Representative ECG trace for P3 control (B) and H2CKO (C) pups. Panel (B) insert represents one cycle of cardiac contraction. Red bars denote the portion of the trace measured for P-wave duration, PR interval, and QRS complex duration as labeled. Control pups averaged 466 bpm, while H2CKO pups averaged 337 bpm (D). P = p-value. Differences in average PR interval (ms), QRS complex duration (ms), and P wave duration (ms) between control and H2CKO P3 pups were not statistically significant (E). Anf ISH in P3 control (F) and H2CKO (G) hearts.