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. 2014 Apr 17;10(4):e1004285. doi: 10.1371/journal.pgen.1004285

Table 4. SNPs showing differential lobular and ductal associations with breast cancer risk in BCAC subjects (ER+ tumours only).

IDC vs Controls* ILC vs Controls** P-het
Cytoband Genes RS number MAF OR (95% CI) P OR (95% CI) P Ductal vs Lobular
1p11.2 rs11249433 0.400 1.09 (1.06, 1.13) 2.3×10−9 1.28 (1.22, 1.35) 7.1×10−20 2.7×10−8
5p12 rs10941679 0.254 1.17 (1.13, 1.21) 4.0×10−21 1.03 (0.97, 1.10) 0.318 1.5×10−4
10q26.13 FGFR2 rs2981579 0.404 1.31 (1.27, 1.35) 1.2×10−71 1.42 (1.35, 1.50) 3.4×10−38 5.3×10−3
14q24.1 RAD51L1 rs2588809 0.158 1.12 (1.08, 1.17) 8.7×10−9 0.99 (0.92, 1.07) 0.870 0.001
10q21.2 ZNF365 rs10995190 0.158 0.87 (0.84, 0.91) 4.1×10−11 0.76 (0.71, 0.83) 1.2×10−11 0.002
8q21.11 rs6472903 0.178 0.89 (0.85, 0.92) 2.9×10−9 1.00 (0.93, 1.07) 0.895 0.004
2q31.1 CDCA7 rs1550623 0.156 0.93 (0.89, 0.96) 2.1×10−4 1.01 (0.94, 1.08) 0.839 0.031

*15023 cases, 29273 controls.

**3201 cases, 29273 controls.