Table 4. Sensitivity and negative predictive value (NPV) at two and 18 months post-treatment.
Test method | Sensitivity (95%CI) | NPV (95%CI) |
Microscopy | ||
Post-treatment (2 month) | 31% (22, 42) | 35% (25, 46) |
Post-treatment (18 month) | 74% (64, 82) | 38% (24, 54) |
Microhaematuria | ||
Post-treatment (2 month) | 33% (23, 44) | 33% (23, 44) |
Post-treatment (18 month) | 53% (43, 63) | 26% (16, 39) |
cSEA-ELISA | ||
Post-treatment (2 month) | 32% (21, 44) | 26% (16, 39) |
Post-treatment (18 month) | 46% (36, 56) | 17% (9, 29) |
Real-time PCR | ||
Post-treatment (2 month) | 95% (88, 99) | 89% (73, 97) |
Post-treatment (18 month) | 92% (85, 96) | 67% (45, 84) |
Note: Real-time PCR and/or microscopy positivity was used as ‘gold standard.’