Figure 2. Genome comparisons between H99 and other Cryptococcus neoformans (JEC21 - A) and Cryptococcus gattii (WM276 - B and R265- C) strains.
Each dot represents the best tBLASTn return in the target genome when a protein sequence of H99 was used as query. The X axis shows the coordinates of the H99 chromosomes anchored on the centromeres at the middle. The Y axis shows the coordinates of the tBLASTn hits on their respective supercontigs/chromosomes in the target genomes. When the two chromosomes under comparison are in synteny, the BLAST hits of that H99 chromosome form a straight line composed by dots of same color (e.g. H99 chromosome 1 in Figure 2A). If there are chromosomal translocations, the BLAST hits of the H99 chromosome are composed of dots with different colors. Additionally, large-scale inversions (>60 kb in size) are highlighted by stars and boxes showing the potential translocations mediated by centromeres (see Results/Discussion). Numbers indicate the chromosomes/supercontigs in the target genome that have undergone translocations relative to the H99 genome.