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. 2014 Apr 17;9(4):e95236. doi: 10.1371/journal.pone.0095236

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© 2014 Dow et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Immunofluorescence stains for GFP and mKate2 in the small intestine and pancreas of ‘no rtTA’, R26-rtTA, CAGs-rtTA3 and CAGs-RIK mice following 1 week of doxycycline treatment. All rtTA strains show strong GFP induction in small intestine (A), but only CAGs-rtTA3 and CAGs-RIK show robust and uniform GFP expression (and mKate2 for RIK) in the pancreatic acinar tissue (B).