Table 1. Single-channel properties of GABA receptors and levamisole-sensitive AChRs.
| Agonist (mM) | O1 (ms) (area) | O2 (ms) (area) | C2 (ms) (area) | n |
| UNC-49 receptors | ||||
| GABA 1 | 0.26±0.04 (1) | nd | 1100±300 (0.85±0.03) | 3 |
| GABA 3 | 0.20±0.03 (1) | nd | 220±140 (0.80±0.07) | 3 |
| GABA 5 | 0.39±0.09 (1) | nd | 180±70 (0.77±0.17) | 9 |
| GABA 10 | 0.18±0.03 (1) | nd | 87±70 (0.85±0.01) | 4 |
| Muscimol 1 | 0.40±0.17 (1) | nd | 950±500 (0.57±0.09) | 5 |
| PZE 10 | 0.40±0.11 (1) | nd | 1900±400 (0.58±0.14) | 5 |
| L-AChRs | ||||
| ACh 0.05 | 0.24±0.03 (0.89±0.01) | 0.40±0.06 (0.11±0.01) | 13.60±6.2 (0.70±0.01) | 5 |
| ACh 0.05 + IVM 0.05 | 0.26±0.07 (0.87±0.08) | 0.41±0.16 (0.17±0.04) | 48.40±20 (0.58±0.11) | 5 |
Single-channel currents were recorded from L1 muscle cells at a holding potential of +100 mV. GABA channels were recorded in the presence of GABA, muscimol and piperazine in the pipette solution. ACh channels corresponding to L-AChRs were recorded in the presence of ACh with and without IVM in both pipette and dish solutions. The data were obtained from the corresponding histograms and correspond to the average of different recordings (n) for each condition. nd: Non detected.